Novak Djokovic, Roger Federer, Andy Murray and Stan Wawrinka can justify their status as Wimbledon’s big four by making the semi-finals on Wednesday.
Defending champion, top seed and 2011 winner Djokovic takes on US Open champion Marin Cilic boasting a 12-0 career lead over the Croatian.
Seven-time champion Federer faces Gilles Simon with the Frenchman playing in his maiden Wimbledon quarter-final while 2013 winner Murray, seeded three, is up against surprise quarter-finalist Vasek Pospisil of Canada.
Fourth seed Wawrinka tackles 2007 semi-finalist Richard Gasquet, the second Frenchman in the last-eight.
Cilic, 26, lost to Djokovic in five sets in the quarter-finals in 2014 despite being two sets to one ahead.
He then went on to win a maiden Grand Slam title at the US Open in September.
“I know him very well. We played many, many matches on different surfaces,” said Djokovic after reaching his seventh successive Wimbledon quarter-final and 25th in a row at the majors with a 6-7 (6/8), 6-7 (6/8), 6-1, 6-4, 7-5 win over Kevin Anderson of South Africa.
Federer, 33, is bidding to become the oldest Wimbledon champion and win a record eighth title. The Swiss has been virtually untroubled on serve on his way to a 13th Wimbledon quarter-final, just one behind the record of 14 held by Jimmy Connors.
He has yet to drop serve, has faced just two break points in 58 service games and has committed only three double faults.
The last time he dropped serve was in the second set of his opening round win over Philipp Kohlschreiber in Halle-more than 100 service games ago.
“Maybe the guys are returning terrible,” joked Federer.
“Gilles Simon is one of the best return players we have in the game. I would think I’ll be tested a lot. So that streak’s maybe coming to an end, in my opinion.”
Simon, one of three over-30s in the last eight, last made the quarter-finals of a Grand Slam in Australia in 2009.
He trails Federer 5-2 in career clashes. After winning their first two meetings in 2008, the Frenchman has lost five in succession although their only two Grand Slam matches-at the 2011 Australian Open and 2013 French Open-went to five sets.
Murray is into his eighth successive Wimbledon quarter-final and takes a 3-0 lead into his match-up with world number 56 Pospisil who had never previously got beyond the third round of a major before this Wimbledon.
